South Amana is an unincorporated community and census-designated place in northern Iowa County, Iowa, United States, and is part of the seven villages of the Amana Colonies. It lies along U.S. Route 6 east of the city of Marengo, the county seat of Iowa County. Its elevation is 778 feet. Although South Amana is unincorporated, it has a post office with the ZIP code of 52334, which opened on 19 June 1874.South Amana was a shipping point on the Chicago, Rock Island and Pacific Railroad.As of the 2010 Census the population of South Amana was 159.